DDS promotes longevity through a microbiome-mediated starvation signal

The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and decreased mitochondrial function. Here we report a...

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Bibliografiske detaljer
Udgivet i:	Transl Med Aging
Main Authors:	Choi, Haeri, Cho, Sung Chun, Ha, Young Wan, Ocampo, Billie, Park, Shirley, Chen, Shiwen, Bennett, Christopher F., Han, Jeehae, Rossner, Ryan, Kang, Jong-Sun, Lee, Yun-ll, Park, Sang Chul, Kaeberlein, Matt
Format:	Artigo
Sprog:	Inglês
Udgivet:	2019
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7080190/ https://ncbi.nlm.nih.gov/pubmed/32190786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tma.2019.07.001
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DDS promotes longevity through a microbiome-mediated starvation signal

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