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Safety and immunogenicity of a potential checkpoint blockade vaccine for canine melanoma

Human immunotherapy with checkpoint blockades has achieved significant breakthroughs in recent years. In this study, a checkpoint blockade vaccine for canine melanoma was tested for safety and immunogenicity. Five healthy adult dogs received a mixture of three replication-defective chimpanzee-derive...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Kurupati, Raj K., Zhou, Xiangyang, Xiang, Zhiquan, Keller, Lorraine H., Ertl, Hildegund C. J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080056/
https://ncbi.nlm.nih.gov/pubmed/30051333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2201-5
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