SUMO fusion system facilitates soluble expression and high production of bioactive human fibroblast growth factor 23 (FGF23)

As a key humoral regulator of phosphate homeostasis and its involvement in the pathogenesis of human disease, human fibroblast growth factor 23 (hFGF23) has become a particularly attractive therapeutic target. To prepare soluble and bioactive recombinant human FGF23 to meet the increasing demand in...

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Detalhes bibliográficos
Publicado no:Appl Microbiol Biotechnol
Main Authors: Liu, Xiaoju, Chen, Yubin, Wu, Xiaoping, Li, Haiyan, Jiang, Chao, Tian, Haishan, Tang, Lu, Wang, Dezhong, Yu, Ting, Li, Xiaokun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Biotechnologically Relevant Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080044/
https://ncbi.nlm.nih.gov/pubmed/22249722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-011-3864-4
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