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Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination

The primary target in multiple sclerosis (MS) is believed to be either myelin itself (myelinopathy) or the myelin-forming cell, the oligodendrocyte (oligodendrogliopathy). Although axonal injury occurs in MS, it is regarded as a secondary event to the myelin damage. Here, the lesion develops from my...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Springer Semin Immunopathol
Hauptverfasser: Tsunoda, Ikuo, Fujinami, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079941/
https://ncbi.nlm.nih.gov/pubmed/12503060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-002-0105-z
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