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Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory

AIM: Active changes in neuronal DNA methylation and demethylation appear to act as controllers of synaptic scaling and glutamate receptor trafficking in learning and memory formation. DNA methyltransferases (DNMTs), including proteins encoded by Dnmt1, Dnmt3a and Dnmt3b, are dominant enzymes carryin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Kong, Qingnuan, Yu, Ming, Zhang, Meng, Wei, Chuang, Gu, Huating, Yu, Shaoyang, Sun, Wei, Li, Nan, Zhou, Yu
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079487/
https://ncbi.nlm.nih.gov/pubmed/32183852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00574-9
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