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Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution
Cancer cell lines are not homogeneous nor are they static in their genetic state and biological properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to the lack of experimental reproducibility frequently observed in tissue-culture-based studies. While cancer ce...
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| Pubblicato in: | NAR Genom Bioinform |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7079336/ https://ncbi.nlm.nih.gov/pubmed/32215369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa016 |
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