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Crystal and solution structures of human oncoprotein Musashi‐2 N‐terminal RNA recognition motif 1

Musashi‐2 (MSI2) belongs to Musashi family of RNA binding proteins (RBP). Like Musashi‐1 (MSI1), it is overexpressed in a variety of cancers and is a promising therapeutic target. Both MSI proteins contain two N‐terminal RNA recognition motifs and play roles in posttranscriptional regulation of targ...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Lan, Lan, Xing, Minli, Kashipathy, Maithri, Douglas, Justin, Gao, Philip, Battaile, Kevin, Hanzlik, Robert, Lovell, Scott, Xu, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079100/
https://ncbi.nlm.nih.gov/pubmed/31603583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25836
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