Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket

RNA-binding protein Musashi-2 (MSI2) is a key regulator in stem cells, it is over-expressed in a variety of cancers and its higher expression is associated with poor prognosis. Like Musashi-1, it contains two N-terminal RRMs (RNA-recognition Motifs, also called RBDs (RNA-binding Domains)), RRM1 and...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lan, Lan, Xing, Minli, Douglas, Justin T., Gao, Philip, Hanzlik, Robert P., Xu, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739758/
https://ncbi.nlm.nih.gov/pubmed/29290973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22540
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