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Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons
The glycoproteins and glycolipids of the cell surface have sugar chains that normally terminate in a sialic acid residue, but inflammatory activation of myeloid cells can cause sialidase enzymes to remove these residues, resulting in desialylation and altered activity of surface receptors, such as t...
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| Publicado no: | Glia |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7079032/ https://ncbi.nlm.nih.gov/pubmed/31774586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23757 |
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