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Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression

Chronic wasting disease (CWD) is a prion disease of free‐ranging and farmed cervids that is highly contagious because of extensive prion shedding and prion persistence in the environment. Previously, cellulose ether compounds (CEs) have been shown to significantly extend the survival of mice inocula...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurochem
Hauptverfasser: Hannaoui, Samia, Arifin, Maria Immaculata, Chang, Sheng Chun, Yu, Jie, Gopalakrishnan, Preetha, Doh‐ura, Katsumi, Schatzl, Hermann M., Gilch, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078990/
https://ncbi.nlm.nih.gov/pubmed/31553058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14877
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