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Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress

Thrombosis is a principle cause of cardiovascular disease, the leading cause of morbidity and mortality worldwide; however, the conventional anti-thrombotic approach often leads to bleeding complications despite extensive clinical management and monitoring. In view of the intense crosstalk between i...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Wu, Hao, Wang, Ying, Zhang, Yupeng, Xu, Feng, Chen, Jiepeng, Duan, Lili, Zhang, Tingting, Wang, Jian, Zhang, Fengjiao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078552/
https://ncbi.nlm.nih.gov/pubmed/32193146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101500
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