Oral high dose vitamin B12 decreases renal superoxide and post-ischemia/reperfusion injury in mice

Renal ischemia/reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI), a potentially fatal syndrome characterized by a rapid decline in kidney function. Excess production of superoxide contributes to the injury. We hypothesized that oral administration of a high dose of vitamin B12...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Li, Feng, Bahnson, Edward M., Wilder, Jennifer, Siletzky, Robin, Hagaman, John, Nickekeit, Volker, Hiller, Sylvia, Ayesha, Azraa, Feng, Lanfei, Levine, Jerrold S., Takahashi, Nobuyuki, Maeda-Smithies, Nobuyo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078436/
https://ncbi.nlm.nih.gov/pubmed/32182573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101504
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