miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction

BACKGROUND & AIMS: Metabolism supports cell proliferation and growth. Surprisingly, the tumor suppressor miR-22 is induced by metabolic stimulators like bile acids. Thus, this study examines whether miR-22 could be a metabolic silencer. METHODS: The relationship between miR-22 and the expression...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Hu, Ying, Liu, Hui-Xin, Jena, Prasant Kuma, Sheng, Lili, Ali, Mohamed R., Wan, Yu-Jui Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078383/
https://ncbi.nlm.nih.gov/pubmed/32195457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100093
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