Interactions of 17β-Hydroxysteroid Dehydrogenase Type 10 and Cyclophilin D in Alzheimer's Disease

The nucleus-encoded 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) regulates cyclophilin D (cypD) in the mitochondrial matrix. CypD regulates opening of mitochondrial permeability transition pores. Both mechanisms may be affected by amyloid β peptides accumulated in mitochondria in Alzheimer&#...

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Bibliografiske detaljer
Udgivet i:Neurochem Res
Main Authors: Kristofikova, Zdenka, Springer, Tomas, Gedeonova, Erika, Hofmannova, Adéla, Ricny, Jan, Hromadkova, Lenka, Vyhnalek, Martin, Laczo, Jan, Nikolai, Tomas, Hort, Jakub, Petrasek, Tomas, Stuchlik, Ales, Vales, Karel, Klaschka, Jan, Homola, Jiri
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078148/
https://ncbi.nlm.nih.gov/pubmed/31997103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-020-02970-y
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