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Advances in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) research

Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is an autosomal dominant hereditary cancer syndrome with incomplete penetrance. It is caused by a germline amorphic allele of the FH gene, which encodes the TCA cycle enzyme, fumarate hydratase (FH). HLRCC patients are genetically predisposed t...

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Publicado en:Semin Cancer Biol
Autor principal: Ooi, Aikseng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078051/
https://ncbi.nlm.nih.gov/pubmed/31689495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2019.10.016
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