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Hereditary leiomyomatosis and renal cell carcinoma

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal-dominant hereditary syndrome, which is caused by germline mutations in the FH gene that encodes the tricarboxylic acid cycle enzyme fumarate hydratase (FH). HLRCC patients are predisposed to develop cutaneous leiomyomas, mult...

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Detalles Bibliográficos
Autores principales: Schmidt, Laura S, Linehan, W Marston
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074185/
https://ncbi.nlm.nih.gov/pubmed/25018647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S42097
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