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Hereditary leiomyomatosis and renal cell carcinoma

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal-dominant hereditary syndrome, which is caused by germline mutations in the FH gene that encodes the tricarboxylic acid cycle enzyme fumarate hydratase (FH). HLRCC patients are predisposed to develop cutaneous leiomyomas, mult...

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Detalhes bibliográficos
Main Authors: Schmidt, Laura S, Linehan, W Marston
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074185/
https://ncbi.nlm.nih.gov/pubmed/25018647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S42097
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