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Identification of Novel RNA Design Candidates by Clustering the Extended RNA-As-Graphs Library

BACKGROUND: We re-evaluate our RNA-As-Graphs clustering approach, using our expanded graph library and new RNA structures, to identify potential RNA-like topologies for design. Our coarse-grained approach represents RNA secondary structures as tree and dual graphs, with vertices and edges correspond...

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Veröffentlicht in:Biochim Biophys Acta Gen Subj
Hauptverfasser: Jain, Swati, Zhu, Qiyao, Paz, Amiel S.P., Schlick, Tamar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078028/
https://ncbi.nlm.nih.gov/pubmed/31954797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129534
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