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Inverse Folding with RNA-As-Graphs Produces a Large Pool of Candidate Sequences with Target Topologies
We present an RNA-As-Graphs (RAG) based inverse folding algorithm, RAG-IF, to design novel RNA sequences that fold onto target tree graph topologies. The algorithm can be used to enhance our recently reported computational design pipeline (Jain et. al, NAR 2018). The RAG approach represents RNA seco...
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| Publicado en: | J Struct Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042079/ https://ncbi.nlm.nih.gov/pubmed/31874236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.107438 |
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