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Computational generation and screening of RNA motifs in large nucleotide sequence pools

Although identification of active motifs in large random sequence pools is central to RNA in vitro selection, no systematic computational equivalent of this process has yet been developed. We develop a computational approach that combines target pool generation, motif scanning and motif screening us...

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Hlavní autoři: Kim, Namhee, Izzo, Joseph A., Elmetwaly, Shereef, Gan, Hin Hark, Schlick, Tamar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910066/
https://ncbi.nlm.nih.gov/pubmed/20448026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq282
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