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Computational generation and screening of RNA motifs in large nucleotide sequence pools

Although identification of active motifs in large random sequence pools is central to RNA in vitro selection, no systematic computational equivalent of this process has yet been developed. We develop a computational approach that combines target pool generation, motif scanning and motif screening us...

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Autors principals: Kim, Namhee, Izzo, Joseph A., Elmetwaly, Shereef, Gan, Hin Hark, Schlick, Tamar
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910066/
https://ncbi.nlm.nih.gov/pubmed/20448026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq282
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