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A computational proposal for designing structured RNA pools for in vitro selection of RNAs

Although in vitro selection technology is a versatile experimental tool for discovering novel synthetic RNA molecules, finding complex RNA molecules is difficult because most RNAs identified from random sequence pools are simple motifs, consistent with recent computational analysis of such sequence...

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Autori principali: Kim, Namhee, Gan, Hin Hark, Schlick, Tamar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831855/
https://ncbi.nlm.nih.gov/pubmed/17322501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.374907
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