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Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell output blocked tremor in mice that were given the...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077982/ https://ncbi.nlm.nih.gov/pubmed/32180549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51928 |
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