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Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation

Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell output blocked tremor in mice that were given the...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Brown, Amanda M, White, Joshua J, van der Heijden, Meike E, Zhou, Joy, Lin, Tao, Sillitoe, Roy V
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077982/
https://ncbi.nlm.nih.gov/pubmed/32180549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51928
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