Generation of Antitumor T Cells For Adoptive Cell Therapy With Artificial Antigen Presenting Cells

Adoptive cell therapy with ex vivo expanded tumor infiltrating lymphocytes or gene engineering T cells expressing chimeric antigen receptors (CAR) is a promising treatment for cancer patients. This production utilizes T-cell activation and transduction with activation beads and RetroNectin, respecti...

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Bibliographic Details
Published in:J Immunother
Main Authors: Shrestha, Bishwas, Zhang, Yongliang, Yu, Bin, Li, Gongbo, Boucher, Justin C., Beatty, Nolan J., Tsai, Ho-Chien, Wang, Xuefeng, Mishra, Asmita, Sweet, Kendra, Lancet, Jeffrey E., Kelley, Linda, Davila, Marco L.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077957/
https://ncbi.nlm.nih.gov/pubmed/31834208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000306
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