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Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue
S100B protein bridges chronic mucosal inflammation and colorectal cancer given its ability to activate NF‐kappaB transcription via RAGE signalling and sequestrate pro‐apoptotic wtp53. Being an S100B inhibitor, pentamidine antagonizes S100B‐wtp53 interaction, restoring wtp53‐mediated pro‐apoptotic co...
Gorde:
| Argitaratua izan da: | J Cell Mol Med |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7077541/ https://ncbi.nlm.nih.gov/pubmed/32022398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14943 |
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