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No Evidence of PGRN or MAPT Gene Dosage Alterations in a Collection of Patients with Frontotemporal Lobar Degeneration

BACKGROUND/AIMS: Alterations in gene dosage have recently been associated with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, and deletions of the progranulin (PGRN) locus were recently described in patients with frontotemporal lobar degeneration (FTLD)....

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Detalhes bibliográficos
Publicado no:Dement Geriatr Cogn Disord
Main Authors: Skoglund, Lena, Ingvast, Sofie, Matsui, Toshifumi, Freeman, Stefanie H., Frosch, Matthew P., Brundin, Rosemarie, Giedraitis, Vilmantas, Growdon, John H., Hyman, Bradley T., Lannfelt, Lars, Ingelsson, Martin, Glaser, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077072/
https://ncbi.nlm.nih.gov/pubmed/19940479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000260046
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