Delayed delivery of endothelial progenitor cell derived extracellular vesicles via shear-thinning gel improves post-infarct hemodynamics

BACKGROUND: EVs are promising therapeutics for cardiovascular disease, but poorly-timed delivery may hinder efficacy. We characterized the time-dependent response to EPC-EVs within an injectable shear-thinning hydrogel (STG+EV) post-MI to identify when an optimal response is achieved. METHODS: The a...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Chung, Jennifer J., Han, Jason, Wang, Leo L., Arisi, Maria F., Zaman, Samir, Gordon, Jonathan, Li, Elizabeth, Kim, Samuel T., Tran, Zoe, Chen, Carol W., Gaffey, Ann C., Burdick, Jason A., Atluri, Pavan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077034/
https://ncbi.nlm.nih.gov/pubmed/31353103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2019.06.017
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