Exosomal miRNA-128-3p from mesenchymal stem cells of aged rats regulates osteogenesis and bone fracture healing by targeting Smad5

Transplantation of mesenchymal stem cells (MSCs) has been considered an effective therapeutic treatment for a variety of diseases including bone fracture. However, there are associated complications along with MSCs transplantation. There is evidence to show that exosomes (Exos) derived from MSCs exe...

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Publicado en:J Nanobiotechnology
Autores principales: Xu, Tao, Luo, Yongjun, Wang, Jiaxing, Zhang, Ning, Gu, Changjiang, Li, Linwei, Qian, Dingfei, Cai, Weihua, Fan, Jin, Yin, Guoyong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077029/
https://ncbi.nlm.nih.gov/pubmed/32178675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00601-w
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