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Functional analysis of Cullin 3 E3 ligases in tumorigenesis

Cullin 3-RING ligases (CRL3) play pivotal roles in the regulation of various physiological and pathological processes, including neoplastic events. The substrate adaptors of CRL3 typically contain a BTB domain that mediates the interaction between Cullin 3 and target substrates to promote their ubiq...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Rev Cancer
Main Authors: Cheng, Ji, Guo, Jianping, Wang, Zhiwei, North, Brian J., Tao, Kaixiong, Dai, Xiangpeng, Wei, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076836/
https://ncbi.nlm.nih.gov/pubmed/29128526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2017.11.001
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