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P-Cresylsulfate, the Protein-Bound Uremic Toxin, Increased Endothelial Permeability Partly Mediated by Src-Induced Phosphorylation of VE-Cadherin

The goal of our study was to investigate the impact of p-cresylsulfate (PCS) on the barrier integrity in human umbilical vein endothelial cell (HUVEC) monolayers and the renal artery of chronic kidney disease (CKD) patients. We measured changes in the transendothelial electrical resistance (TEER) of...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Chen, Shih-Chieh, Huang, Shin-Yin, Wu, Chia-Chun, Hsu, Chiung-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076797/
https://ncbi.nlm.nih.gov/pubmed/31973024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12020062
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