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P-Cresylsulfate, the Protein-Bound Uremic Toxin, Increased Endothelial Permeability Partly Mediated by Src-Induced Phosphorylation of VE-Cadherin

The goal of our study was to investigate the impact of p-cresylsulfate (PCS) on the barrier integrity in human umbilical vein endothelial cell (HUVEC) monolayers and the renal artery of chronic kidney disease (CKD) patients. We measured changes in the transendothelial electrical resistance (TEER) of...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Chen, Shih-Chieh, Huang, Shin-Yin, Wu, Chia-Chun, Hsu, Chiung-Fang
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076797/
https://ncbi.nlm.nih.gov/pubmed/31973024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12020062
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