MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles

Remyelination is a key aspect in multiple sclerosis pathology and a special effort is being made to promote it. However, there is still no available treatment to regenerate myelin and several strategies are being scrutinized. Myelination is naturally performed by oligodendrocytes and microRNAs have...

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Udgivet i:Pharmaceutics
Main Authors: Osorio-Querejeta, Iñaki, Carregal-Romero, Susana, Ayerdi-Izquierdo, Ana, Mäger, Imre, Nash, Leslie A., Wood, Matthew, Egimendia, Ander, Betanzos, M., Alberro, Ainhoa, Iparraguirre, Leire, Moles, Laura, Llarena, Irantzu, Möller, Marco, Goñi-de-Cerio, Felipe, Bijelic, Goran, Ramos-Cabrer, Pedro, Muñoz-Culla, Maider, Otaegui, David
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076664/
https://ncbi.nlm.nih.gov/pubmed/32098213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020186
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