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Formulating a Stable Mannitol Infusion while Maintaining Hyperosmolarity

Mannitol infusion is commonly used in the treatment of intracranial hypertension following traumatic brain injury. It has long been known to have stability issues, specifically, mannitol recrystallises from solutions greater than 10% w/v in ambient conditions. This can happen at any time, whether on...

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Foilsithe in:Pharmaceutics
Main Authors: Kavanagh, Oisín, Hogan, Fiona, Murphy, Caoimhe, Croker, Denise, Walker, Gavin
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076636/
https://ncbi.nlm.nih.gov/pubmed/32098214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020187
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