Tablets of “Hydrochlorothiazide in Cyclodextrin in Nanoclay”: A New Nanohybrid System with Enhanced Dissolution Properties

Hydrochlorothiazide (HCT), a Biopharmaceutical Classification System (BCS) class IV drug, is characterized by low solubility and permeability, that negatively affect its oral bioavailability, reducing its therapeutic efficacy. The combined use of cyclodextrins (CDs) and nanoclays (NCs) recently prov...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Maestrelli, Francesca, Cirri, Marzia, García-Villén, Fátima, Borrego-Sánchez, Ana, Viseras Iborra, César, Mura, Paola
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076548/
https://ncbi.nlm.nih.gov/pubmed/32013051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020104
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