Tablets of “Hydrochlorothiazide in Cyclodextrin in Nanoclay”: A New Nanohybrid System with Enhanced Dissolution Properties

Hydrochlorothiazide (HCT), a Biopharmaceutical Classification System (BCS) class IV drug, is characterized by low solubility and permeability, that negatively affect its oral bioavailability, reducing its therapeutic efficacy. The combined use of cyclodextrins (CDs) and nanoclays (NCs) recently prov...

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Publicat a:Pharmaceutics
Autors principals: Maestrelli, Francesca, Cirri, Marzia, García-Villén, Fátima, Borrego-Sánchez, Ana, Viseras Iborra, César, Mura, Paola
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076548/
https://ncbi.nlm.nih.gov/pubmed/32013051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020104
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