Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines

We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for site-specific targeting of human epithelial gro...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Souto, Eliana B., Souto, Selma B., Zielinska, Aleksandra, Durazzo, Alessandra, Lucarini, Massimo, Santini, Antonello, Horbańczuk, Olaf K., Atanasov, Atanas G., Marques, Conrado, Andrade, Luciana N., Silva, Amélia M., Severino, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076521/
https://ncbi.nlm.nih.gov/pubmed/32079103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020161
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