(+)-Limonene 1,2-Epoxide-Loaded SLNs: Evaluation of Drug Release, Antioxidant Activity, and Cytotoxicity in an HaCaT Cell Line

In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1,2-epoxide and glycerol monostearate (Lim-SLNs), stabilized with Poloxamer(®) 188 in aqueous dispersion to modify the release profile of the loaded monoterpene derivative. We also evaluated the role of SLNs in...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Souto, Eliana B., Zielinska, Aleksandra, Souto, Selma B., Durazzo, Alessandra, Lucarini, Massimo, Santini, Antonello, Silva, Amélia M., Atanasov, Atanas G., Marques, Conrado, Andrade, Luciana N., Severino, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073088/
https://ncbi.nlm.nih.gov/pubmed/32093358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041449
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