Generation and validation of a PITX2–EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells

PITX2 (Paired-like homeodomain transcription factor 2) plays important roles in asymmetric development of the internal organs and symmetric development of eye tissues. During eye development, cranial neural crest cells migrate from the neural tube and form the periocular mesenchyme (POM). POM cells...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Okubo, Toru, Hayashi, Ryuhei, Shibata, Shun, Kudo, Yuji, Ishikawa, Yuki, Inoue, Saki, Kobayashi, Yuki, Honda, Ai, Honma, Yoichi, Kawasaki, Satoshi, Nishida, Kohji
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076207/
https://ncbi.nlm.nih.gov/pubmed/32034090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010713
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