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Ocular surface ectoderm instigated by WNT inhibition and BMP4

We sought to elucidate how and when the ocular surface ectoderm commits to its differentiation into the corneal epithelium in eye development from human induced pluripotent stem cells (hiPSCs) under the influence of WNT signaling and the actions of BMP4. These signals are key drivers ocular surface...

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Publicat a:Stem Cell Res
Autors principals: Kobayashi, Yuki, Hayashi, Ryuhei, Shibata, Shun, Quantock, Andrew J., Nishida, Kohji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347012/
https://ncbi.nlm.nih.gov/pubmed/32603880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2020.101868
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