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Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals

The pathogenesis of many human diseases has been attributed to the over production of reactive oxygen species (ROS), particularly superoxide (O(2)(●-)) and hydrogen peroxide (H(2)O(2)), by-products of metabolism that are generated by the premature reaction of electrons with molecular oxygen (O(2)) b...

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Pubblicato in:Redox Biol
Autore principale: Mailloux, Ryan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076094/
https://ncbi.nlm.nih.gov/pubmed/32171726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101472
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