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Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action
A highly expressed prostaglandin E(2) (PGE(2)) in tumor tissues suppresses antitumor immunity in the tumor microenvironment (TME) and causes tumor immune evasion leading to disease progression. In animal studies, selective inhibition of the prostaglandin E receptor 4 (EP4), one of four PGE(2) recept...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7076081/ https://ncbi.nlm.nih.gov/pubmed/32210957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00324 |
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