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Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action
A highly expressed prostaglandin E(2) (PGE(2)) in tumor tissues suppresses antitumor immunity in the tumor microenvironment (TME) and causes tumor immune evasion leading to disease progression. In animal studies, selective inhibition of the prostaglandin E receptor 4 (EP4), one of four PGE(2) recept...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7076081/ https://ncbi.nlm.nih.gov/pubmed/32210957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00324 |
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