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Striated myocyte structural integrity: Automated analysis of sarcomeric z-discs

As sarcomeres produce the force necessary for contraction, assessment of sarcomere order is paramount in evaluation of cardiac and skeletal myocytes. The uniaxial force produced by sarcomeres is ideally perpendicular to their z-lines, which couple parallel myofibrils and give cardiac and skeletal my...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Morris, Tessa Altair, Naik, Jasmine, Fibben, Kirby Sinclair, Kong, Xiangduo, Kiyono, Tohru, Yokomori, Kyoko, Grosberg, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075639/
https://ncbi.nlm.nih.gov/pubmed/32130207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007676
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