Biochemical and immunological characterization of an ETEC CFA/I adhesin cholera toxin B subunit chimera

Surface-expressed colonization factors and their subunits are promising candidates for inclusion into a multivalent vaccine targeting enterotoxigenic Escherichia coli (ETEC), a leading cause of acute bacterial diarrhea in developing regions. However, soluble antigens are often poorly immunogenic in...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jobling, Michael G., Poole, Steven T., Rasulova-Lewis, Fatima, O’Dowd, Aisling, McVeigh, Annette L., Balakrishnan, Amit, Sincock, Stephanie A., Prouty, Michael G., Holmes, Randall K., Savarino, Stephen J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075575/
https://ncbi.nlm.nih.gov/pubmed/32176708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230138
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