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Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart

Store-operated Ca(2+) entry (SOCE) is an essential Ca(2+) signaling mechanism present in most animal cells. SOCE refers to Ca(2+) influx that is activated by depletion of sarco/endoplasmic reticulum (S/ER) Ca(2+) stores. The main components of SOCE are STIM and Orai. STIM proteins function as S/ER C...

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Vydáno v:Biol Open
Hlavní autoři: Petersen, Courtney E., Wolf, Matthew J., Smyth, Jeremy T.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075072/
https://ncbi.nlm.nih.gov/pubmed/32086252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.049999
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