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Phosphorylation of STIM1 Underlies Suppression of Store-operated Calcium Entry During Mitosis

Store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) currents (I(crac)) are strongly suppressed during mitosis, the only known physiological situation in which Ca(2+) store depletion is uncoupled from the activation of Ca(2+) influx. We found that the ER Ca(2+) sensor, STIM1, faile...

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Detalhes bibliográficos
Main Authors: Smyth, Jeremy T., Petranka, John G., Boyles, Rebecca R., DeHaven, Wayne I., Fukushima, Miwako, Johnson, Katina L., Williams, Jason G., Putney, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552519/
https://ncbi.nlm.nih.gov/pubmed/19881501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1995
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