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DTD: An R Package for Digital Tissue Deconvolution

Digital tissue deconvolution (DTD) estimates the cellular composition of a tissue from its bulk gene-expression profile. For this, DTD approximates the bulk as a mixture of cell-specific expression profiles. Different tissues have different cellular compositions, with cells in different activation s...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Schön, Marian, Simeth, Jakob, Heinrich, Paul, Görtler, Franziska, Solbrig, Stefan, Wettig, Tilo, Oefner, Peter J., Altenbuchinger, Michael, Spang, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074920/
https://ncbi.nlm.nih.gov/pubmed/31995409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0469
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