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Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice

Microglia, the resident macrophages, act as the first and main form of active immune defense in the central nervous system. Arginase 2 (Arg2) is an enzyme involved in L-arginine metabolism and is expressed in macrophages and nervous tissue. In this study, we determined whether the absence of Arg2 pl...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Yin, Yuhua, Phạm, Thuỳ Linh, Shin, Juhee, Shin, Nara, Kang, Dong-Wook, Lee, Sun Yeul, Lee, Wonhyung, Kim, Cuk-Seong, Kim, Sang Ryong, Hong, Jinpyo, Kim, Dong-Woon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073606/
https://ncbi.nlm.nih.gov/pubmed/31979015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9020305
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