Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1

Neurofibromatosis type 1 (NF1) is a monogenic syndrome that gives rise to numerous symptoms including cognitive impairment, skeletal abnormalities, and growth of benign nerve sheath tumors. Nearly all NF1 patients develop cutaneous neurofibromas (cNFs), which occur on the skin surface, whereas 40–60...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Banerjee, Jineta, Allaway, Robert J, Taroni, Jaclyn N, Baker, Aaron, Zhang, Xiaochun, Moon, Chang In, Pratilas, Christine A, Blakeley, Jaishri O, Guinney, Justin, Hirbe, Angela, Greene, Casey S, Gosline, Sara JC
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073563/
https://ncbi.nlm.nih.gov/pubmed/32098059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020226
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