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Recent insights into mechanisms of β-cell lipo- and glucolipotoxicity in type 2 diabetes
The deleterious effects of chronically elevated free fatty acid (FFA) levels on glucose homeostasis are referred to as lipotoxicity, and the concurrent exposure to high glucose may cause synergistic glucolipotoxicity. Lipo- and glucolipotoxicity have been studied for over 25 years. Here, we review t...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073302/ https://ncbi.nlm.nih.gov/pubmed/31628942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.09.016 |
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