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Effects of tobacco smoking on the tumor immune microenvironment in head and neck squamous cell carcinoma

PURPOSE: Patients with head and neck squamous cell carcinoma (HNSCC) who actively smoke during treatment have worse survival compared to never-smokers and former-smokers. We hypothesize the poor prognosis in tobacco smokers with HNSCC is, at least in part, due to ongoing suppression of immune respon...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: de la Iglesia, Janis V., Slebos, Robbert J.C., Martin-Gomez, Laura, Wang, Xuefeng, Teer, Jamie K., Tan, Aik Choon, Gerke, Travis A., Aden-Buie, Garrick, Van Veen, Tessa, Masannat, Jude, Chaudhary, Ritu, Song, Feifei, Fournier, Michelle, Siegel, Erin M., Schabath, Matthew B., Wadsworth, J. Trad, Caudell, Jimmy, Harrison, Louis, Wenig, Bruce M., Conejo-Garcia, Jose, Hernandez-Prera, Juan C., Chung, Christine H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073297/
https://ncbi.nlm.nih.gov/pubmed/31848186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1769
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