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Preclinical immunoPET imaging of glioblastoma-infiltrating myeloid cells using Zirconium-89-labeled anti-CD11b antibody

PURPOSE: Glioblastoma is a lethal brain tumor, heavily infiltrated by tumor-associated myeloid cells (TAMCs). TAMCs are emerging as a promising therapeutic target as they suppress anti-tumor immune responses and promote tumor cell growth. Quantifying TAMCs using non-invasive immunoPET could facilita...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Nigam, Shubhanchi, McCarl, Lauren, Kumar, Rajeev, Edinger, Robert S., Kurland, Brenda F., Anderson, Carolyn J., Panigrahy, Ashok, Kohanbash, Gary, Edwards, W. Barry
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073275/
https://ncbi.nlm.nih.gov/pubmed/31529407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-019-01427-1
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